产品货号：
Z10809
中文名称：
Angiotensinogen/AGT抗体
英文名称：
Anti-Angiotensinogen/AGT Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Angiotensinogen/AGT Antibody |
| 指标别名 | AGT;SERPINA8;Angiotensinogen;Serpin A8;Cleaved into:Angiotensin-1;Angiotensin 1-10;Angiotensin I;Ang I;Angiotensin-2;Angiotensin 1-8;Angiotensin II;Ang II;Angiotensin-3;Angiotensin 2-8;Angiotensin III;Ang III;Des-Asp[1]-angiotensin II;Angiotensin-4;Angiotensin 3-8;Angiotensin IV;Ang IV;Angiotensin 1-9;Angiotensin 1-7;Angiotensin 1-5;Angiotensin 1-4 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM(Intracellular),Direct ELISA |
| 基因名称 | AGT |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Angiotensinogen/AGT recombinant protein (Position:D273-R458). |
| 实际分子量 | 53KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | AGT(ANGIOTENSINOGEN),also called SERPINA8,is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver.ATG is a member of the serpin family,although it is not known to inhibit other enzymes,unlike most serpins.Angiotensinogen is also known as renin substrate.The AGT gene is mapped on 1q42.2.And the human angiotensinogen gene contains 5 exons.The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue.Mutations in this AGT gene are associated with susceptibility to essential hypertension,and can cause renal tubular dysgenesis,a severe disorder of renal tubular development.Defects in this gene have also been associated with non-familial structural atrial fibrillation,and inflammatory bowel disease. |
| Uniprot ID | P01019 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | angiotensinogen |
| 蛋白名全称 | Angiotensinogen |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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